Preclinical and Clinical Evaluation of Intraductally Administered Agents in Early Breast Cancer

Most breast cancers originate in the epithelial cells lining the breast ducts. Intraductal administration of cancer therapeutics would lead to high drug exposure to ductal cells and eliminate preinvasive neoplasms while limiting systemic exposure. We performed preclinical studies in N-methyl-N’-nitr...

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Detalhes bibliográficos
Main Authors: Stearns, Vered, Mori, Tsuyoshi, Jacobs, Lisa K., Khouri, Nagi F., Gabrielson, Edward, Yoshida, Takahiro, Kominsky, Scott L., Huso, David L., Jeter, Stacie, Powers, Penny, Tarpinian, Karineh, Brown, Regina J., Lange, Julie R., Rudek, Michelle A., Zhang, Zhe, Tsangaris, Theodore N., Sukumar, Saraswati
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616888/
https://ncbi.nlm.nih.gov/pubmed/22030751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3002368
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