Phase II study of carboplatin, irinotecan, and bevacizumab for bevacizumab naïve, recurrent glioblastoma

We evaluated the efficacy of carboplatin, irinotecan, and bevacizumab among bevacizumab-naïve, recurrent glioblastoma (GBM) patients in a phase 2, open-label, single arm trial. Forty eligible patients received carboplatin (area under the plasma curve [AUC] 4 mg/ml-min) on day one, while bevacizumab...

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Hauptverfasser: Reardon, David A., Desjardins, Annick, Peters, Katherine B., Gururangan, Sridharan, Sampson, John H., McLendon, Roger E., Herndon, James E., Bulusu, Anuradha, Threatt, Stevie, Friedman, Allan H., Vredenburgh, James J., Friedman, Henry S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616617/
https://ncbi.nlm.nih.gov/pubmed/21986722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-011-0722-2
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