DARPin-targeting of Measles Virus: Unique Bispecificity, Effective Oncolysis, and Enhanced Safety

Oncolytic virotherapy is an emerging treatment modality that uses replication-competent viruses to destroy cancers. Many naturally occurring viruses have a preferential, although nonexclusive, tropism for tumors and tumor cells. In addition, specific targeting of cancer cells can be achieved at the...

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Detalhes bibliográficos
Main Authors: Friedrich, Katrin, Hanauer, Jan RH, Prüfer, Steffen, Münch, Robert C, Völker, Iris, Filippis, Christodoulos, Jost, Christian, Hanschmann, Kay-Martin, Cattaneo, Roberto, Peng, Kah-Whye, Plückthun, Andreas, Buchholz, Christian J, Cichutek, Klaus, Mühlebach, Michael D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616535/
https://ncbi.nlm.nih.gov/pubmed/23380817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.16
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