A carregar...

Rigidity of the extracellular part of HER2: Evidence from engineering subdomain interfaces and shared‐helix DARPin‐DARPin fusions

The second member of the human ErbB family of receptor tyrosine kinases, HER2/hErbB2, is regarded as an exceptional case: The four extracellular subdomains could so far only be found in one fixed overall conformation, designated “open” and resembling the ligand‐bound form of the other ErbB receptors...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Jost, Christian, Stüber, Jakob C., Honegger, Annemarie, Wu, Yufan, Batyuk, Alexander, Plückthun, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563139/
https://ncbi.nlm.nih.gov/pubmed/28639341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3216
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!