טוען...
Frequent homozygous deletion of the LKB1/STK11 gene in non-small cell lung cancer
LKB1/STK11 is a tumor suppressor and a negative regulator of mammalian target of rapamycin signaling. It is inactivated in 30% of lung cancer cell lines but only 5–15% of primary lung adenocarcinomas. There is evidence that homozygous deletion (HD) of chromosome 19p at the LKB locus contributes to t...
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| Main Authors: | , , , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2011
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3616488/ https://ncbi.nlm.nih.gov/pubmed/21532627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.98 |
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