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STK11 (LKB1) mutations in metastatic NSCLC: Prognostic value in the real world

BACKGROUND: Mutations in STK11 (STK11m) and frequently co-occurring KRAS mutations (KRASm/STK11m) are associated with poor survival in metastatic NSCLC (mNSCLC) immuno-oncology trials. There are limited data regarding the prognostic significance of these mutations in a real-world setting. METHODS: T...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Shire, Norah J., Klein, Alyssa B., Golozar, Asieh, Collins, Jenna M., Fraeman, Kathy H., Nordstrom, Beth L., McEwen, Robert, Hembrough, Todd, Rizvi, Naiyer A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470384/
https://ncbi.nlm.nih.gov/pubmed/32881920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0238358
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