SMAD6 Contributes to Patient Survival in Non–Small Cell Lung Cancer and Its Knockdown Reestablishes TGF-β Homeostasis in Lung Cancer Cells

The malignant transformation in several types of cancer, including lung cancer, results in a loss of growth inhibition by transforming growth factor-β (TGF-β). Here, we show that SMAD6 expression is associated with a reduced survival in lung cancer patients. Short hairpin RNA (shRNA)–mediated knockd...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Jeon, Hyo-Sung, Dracheva, Tatiana, Yang, Sei-Hoon, Meerzaman, Daoud, Fukuoka, Junya, Shakoori, Abbas, Shilo, Konstantin, Travis, William D., Jen, Jin
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617041/
https://ncbi.nlm.nih.gov/pubmed/19047146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-1083
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk