XBP-1u suppresses autophagy by promoting the degradation of FoxO1 in cancer cells

Autophagy is activated to maintain cellular energy homeostasis in response to nutrient starvation. However, autophagy is not persistently activated, which is poorly understood at a mechanistic level. Here, we report that turnover of FoxO1 is involved in the dynamic autophagic process caused by gluta...

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Detalhes bibliográficos
Main Authors: Zhao, Ying, Li, Xue, Cai, Mu-Yan, Ma, Ke, Yang, Jing, Zhou, Jingyi, Fu, Wan, Wei, Fu-Zheng, Wang, Lina, Xie, Dan, Zhu, Wei-Guo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616429/
https://ncbi.nlm.nih.gov/pubmed/23277279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.2
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