XBP-1u suppresses autophagy by promoting the degradation of FoxO1 in cancer cells

Autophagy is activated to maintain cellular energy homeostasis in response to nutrient starvation. However, autophagy is not persistently activated, which is poorly understood at a mechanistic level. Here, we report that turnover of FoxO1 is involved in the dynamic autophagic process caused by gluta...

Full description

Saved in:
Bibliographic Details
Main Authors: Zhao, Ying, Li, Xue, Cai, Mu-Yan, Ma, Ke, Yang, Jing, Zhou, Jingyi, Fu, Wan, Wei, Fu-Zheng, Wang, Lina, Xie, Dan, Zhu, Wei-Guo
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2013
Subjects:
Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616429/
https://ncbi.nlm.nih.gov/pubmed/23277279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.2
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items