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XBP1-FoxO1 interaction regulates ER stress-induced autophagy in auditory cells

The purpose of this study was to clarify the relationship among X-box-binding protein 1 unspliced, spliced (XBP1u, s), Forkhead box O1 (FoxO1) and autophagy in the auditory cells under endoplasmic reticulum (ER) stress. In addition, the relationship between ER stress that causes unfolded protein res...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Kishino, Akihiro, Hayashi, Ken, Hidai, Chiaki, Masuda, Takeshi, Nomura, Yasuyuki, Oshima, Takeshi
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5493624/
https://ncbi.nlm.nih.gov/pubmed/28667325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02960-1
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