Genomic assessment of a multikinase inhibitor, sorafenib, in a rodent model of pulmonary hypertension

Pulmonary hypertension (PH) and cancer pathology share growth factor- and MAPK stress-mediated signaling pathways resulting in endothelial and smooth muscle cell dysfunction and angioproliferative vasculopathy. In this study, we assessed sorafenib, an antineoplastic agent and inhibitor of multiple k...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Moreno-Vinasco, Liliana, Gomberg-Maitland, Mardi, Maitland, Michael L., Desai, Ankit A., Singleton, Patrick A., Sammani, Saad, Sam, Lee, Liu, Yang, Husain, Aliya N., Lang, Roberto M., Ratain, Mark J., Lussier, Yves A., Garcia, Joe G. N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616402/
https://ncbi.nlm.nih.gov/pubmed/18303084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00169.2007
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados