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Genomic assessment of a multikinase inhibitor, sorafenib, in a rodent model of pulmonary hypertension
Pulmonary hypertension (PH) and cancer pathology share growth factor- and MAPK stress-mediated signaling pathways resulting in endothelial and smooth muscle cell dysfunction and angioproliferative vasculopathy. In this study, we assessed sorafenib, an antineoplastic agent and inhibitor of multiple k...
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| Autori principali: | , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3616402/ https://ncbi.nlm.nih.gov/pubmed/18303084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00169.2007 |
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