AMPK regulates energy expenditure by modulating NAD(+) metabolism and SIRT1 activity

AMP-activated protein kinase (AMPK) is a metabolic fuel gauge conserved along the evolutionary scale in eukaryotes that senses changes in the intracellular AMP/ATP ratio(1). The interest in AMPK has recently been raised by evidence showing that AMPK plays an important role to explain the therapeutic...

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Detalhes bibliográficos
Main Authors: Cantó, Carles, Gerhart-Hines, Zachary, Feige, Jerome N., Lagouge, Marie, Noriega, Liliana, Milne, Jill C., Elliott, Peter J., Puigserver, Pere, Auwerx, Johan
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616311/
https://ncbi.nlm.nih.gov/pubmed/19262508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07813
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