Pasireotide is more effective than Octreotide in reducing hepato-renal cystogenesis in rodents with polycystic kidney and liver diseases

In polycystic liver (PLD) and kidney (PKD) diseases, increased cAMP levels trigger hepato-renal cystogenesis. We previously reported that reduction of elevated cAMP by targeting somatostatin receptors (SSTRs) with Octreotide (OCT; a somatostatin analogue that preferentially binds to SSTR2), inhibits...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Masyuk, Tatyana V, Radtke, Brynn N, Stroope, Angela J, Banales, Jesús M, Gradilone, Sergio A, Huang, Bing, Masyuk, Anatoliy I, Hogan, Marie C, Torres, Vicente E, LaRusso, Nicholas F
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616157/
https://ncbi.nlm.nih.gov/pubmed/23172758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26140
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items