Amplification of the multidrug resistance gene pfmdr1 in Plasmodium falciparum has arisen as multiple independent events.

The multidrug resistance (MDR) phenotype in mammalian tumor cells can involve amplification of mdr genes that results in overexpression of the protein product termed P-glycoprotein. Chloroquine resistance (CQR) in Plasmodium falciparum has similarities with the MDR phenotype in tumor cells, and some...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Triglia, T, Foote, S J, Kemp, D J, Cowman, A F
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 1991
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361573/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1922044/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.10.5244
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