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pfmdr1 Amplification Is Related to Increased Plasmodium falciparum In Vitro Sensitivity to the Bisquinoline Piperaquine

The 4-aminoquinoline bisquinoline piperaquine is an important partner drug in one of the presently recommended artemisinin combination therapies. Recent clinical trials have confirmed its high efficacy in combination with dihydroartemisinin. Resistance to piperaquine alone has, however, been documen...

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Главные авторы: Veiga, M. I., Ferreira, P. E., Malmberg, M., Jörnhagen, L., Björkman, A., Nosten, F., Gil, J. P.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393437/
https://ncbi.nlm.nih.gov/pubmed/22508315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.06350-11
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