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Role of pfmdr1 Amplification and Expression in Induction of Resistance to Artemisinin Derivatives in Plasmodium falciparum

Artemisinin and its derivatives are the most rapidly acting and efficacious antimalarial drugs currently available. Although resistance to these drugs has not been documented, there is growing concern about the potential for resistance to develop. In this paper we report the selection of parasite re...

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Detalhes bibliográficos
Main Authors: Chavchich, Marina, Gerena, Lucia, Peters, Jennifer, Chen, Nanhua, Cheng, Qin, Kyle, Dennis E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876417/
https://ncbi.nlm.nih.gov/pubmed/20350946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00947-09
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