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Role of pfmdr1 Amplification and Expression in Induction of Resistance to Artemisinin Derivatives in Plasmodium falciparum

Artemisinin and its derivatives are the most rapidly acting and efficacious antimalarial drugs currently available. Although resistance to these drugs has not been documented, there is growing concern about the potential for resistance to develop. In this paper we report the selection of parasite re...

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Autors principals: Chavchich, Marina, Gerena, Lucia, Peters, Jennifer, Chen, Nanhua, Cheng, Qin, Kyle, Dennis E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876417/
https://ncbi.nlm.nih.gov/pubmed/20350946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00947-09
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