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Artemisinin induced dormancy in Plasmodium falciparum: Duration, recovery rates and implications in treatment failure

BACKGROUND: Despite the remarkable activity of artemisinin and its derivatives their monotherapy has been associated with high rates of recrudescence. The temporary growth arrest of ring stage parasites (dormancy) following exposure to artemisinin drugs provides a plausible explanation for this phen...

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Autors principals: Teuscher, Franka, Gatton, Michelle L., Chen, Nanhua, Peters, Jennifer, Kyle, Dennis E., Cheng, Qin
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949454/
https://ncbi.nlm.nih.gov/pubmed/20863228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/656476
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