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CONTROL OF TUMOR BIOENERGETICS AND SURVIVAL STRESS SIGNALING BY MITOCHONDRIAL HSP90s
Tumors successfully adapt to constantly changing intra- and extra-cellular environments, but the wirings of this process are still largely elusive. Here, we show that Heat Shock Protein 90 (HSP90)-directed protein folding in mitochondria, but not cytosol, maintains energy production in tumor cells....
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| Main Authors: | , , , , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3615709/ https://ncbi.nlm.nih.gov/pubmed/22975376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2012.07.015 |
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