Retrovirus-induced insertional mutagenesis: mechanism of collagen mutation in Mov13 mice.

The Mov13 mouse strain carries a mutation in the alpha 1(I) procollagen gene which is due to the insertion of a Moloney murine leukemia provirus into the first intron. This insertion results in the de novo methylation of the provirus and flanking DNA, the alteration of chromatin structure, and the t...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Barker, D D, Wu, H, Hartung, S, Breindl, M, Jaenisch, R
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 1991
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361539/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1922037/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.10.5154-5163.1991
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