Human-mouse interspecies collagen I heterotrimer is functional during embryonic development of Mov13 mutant mouse embryos.

To investigate whether the human pro alpha 1(I) collagen chain could form an in vivo functional interspecies heterotrimer with the mouse pro alpha 2(I) collagen chain, we introduced the human COL1A1 gene into Mov13 mice which have a functional deletion of the endogenous COL1A1 gene. Transgenic mouse...

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Bibliographic Details
Main Authors: Wu, H, Bateman, J F, Schnieke, A, Sharpe, A, Barker, D, Mascara, T, Eyre, D, Bruns, R, Krimpenfort, P, Berns, A
Format: Artigo
Language:Inglês
Published: 1990
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC362247/
https://ncbi.nlm.nih.gov/pubmed/1690840
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