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Retrovirus-induced insertional mutagenesis: mechanism of collagen mutation in Mov13 mice.

The Mov13 mouse strain carries a mutation in the alpha 1(I) procollagen gene which is due to the insertion of a Moloney murine leukemia provirus into the first intron. This insertion results in the de novo methylation of the provirus and flanking DNA, the alteration of chromatin structure, and the t...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Barker, D D, Wu, H, Hartung, S, Breindl, M, Jaenisch, R
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1991
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361539/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1922037/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.10.5154-5163.1991
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