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Imprinted DNA methylation of the H19 ICR is established and maintained in vivo in the absence of Kaiso

Abstract Background Paternal allele-specific DNA methylation of the imprinting control region (H19 ICR) controls genomic imprinting at the Igf2/H19 locus. We previously demonstrated that the mouse H19 ICR transgene acquires imprinted DNA methylation in preimplantation mouse embryos. This activity is...

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Principais autores: Hitomi Matsuzaki, Minami Kimura, Mizuki Morihashi, Keiji Tanimoto
Format: Artigo
Jezik:Inglês
Izdano: BMC 2024-06-01
Serija:Epigenetics & Chromatin
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Online dostop:https://doi.org/10.1186/s13072-024-00544-8
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