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IFN-γ suppresses permissive chromatin remodeling in the regulatory region of the Il4 Gene
In order to develop the most effective T helper type-1 (Th1) immunity, naïve CD4(+) T cells must acquire the capacity to express IFN-γ while silencing T helper type-2 (Th2) cytokine-producing potential. An Il4 gene silencer has been described. However, it is not completely understood how the silence...
Tallennettuna:
| Päätekijät: | , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3615094/ https://ncbi.nlm.nih.gov/pubmed/23490416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2013.02.010 |
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