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Interferon regulatory factor modulation underlies the bystander suppression of malaria antigen-driven IL-12 and IFN-γ in filaria–malaria co-infection

In areas where polyparasitism is highly prevalent, the impact of multiple parasites on the host response is underestimated. In particular, the presence of helminth infection coincident with malaria profoundly alters the production of malaria-specific IFN-γ, IL-12p70, CXCL9, CXCL10 and CXCL11, cytoki...

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Detalhes bibliográficos
Main Authors: Metenou, Simon, Kovacs, Michael, Dembele, Benoit, Coulibaly, Yaya I., Klion, Amy D., Nutman, Thomas B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430845/
https://ncbi.nlm.nih.gov/pubmed/22213332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201141991
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