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Interferon regulatory factor modulation underlies the bystander suppression of malaria antigen-driven IL-12 and IFN-γ in filaria–malaria co-infection

In areas where polyparasitism is highly prevalent, the impact of multiple parasites on the host response is underestimated. In particular, the presence of helminth infection coincident with malaria profoundly alters the production of malaria-specific IFN-γ, IL-12p70, CXCL9, CXCL10 and CXCL11, cytoki...

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Autores principales: Metenou, Simon, Kovacs, Michael, Dembele, Benoit, Coulibaly, Yaya I., Klion, Amy D., Nutman, Thomas B.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430845/
https://ncbi.nlm.nih.gov/pubmed/22213332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201141991
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