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Gamma Interferon (IFN-γ) and IFN-γ-Inducing Cytokines Interleukin-12 (IL-12) and IL-18 Do Not Augment Infection-Stimulated Bone Resorption In Vivo

Periapical granulomas are induced by bacterial infection of the dental pulp and result in destruction of the surrounding alveolar bone. In previous studies we have reported that the bone resorption in this model is primarily mediated by macrophage-expressed interleukin-1 (IL-1). The expression and a...

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Autors principals: Sasaki, Hajime, Balto, Khaled, Kawashima, Nobuyuki, Eastcott, Jean, Hoshino, Katsuaki, Akira, Shizuo, Stashenko, Philip
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC321357/
https://ncbi.nlm.nih.gov/pubmed/14715554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.11.1.106-110.2004
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