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Molecular Karyotyping of Human Single Sperm by Array- Comparative Genomic Hybridization

No valid method is currently available to analyze the entire genome of sperm, including aneuploidies and structural chromosomal alterations. Here we describe the optimization and application of array-Comparative Genomic Hybridization (aCGH) on single human sperm. The aCGH procedure involves screenin...

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Detalhes bibliográficos
Main Authors: Patassini, Cristina, Garolla, Andrea, Bottacin, Alberto, Menegazzo, Massimo, Speltra, Elena, Foresta, Carlo, Ferlin, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614952/
https://ncbi.nlm.nih.gov/pubmed/23565289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060922
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