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Molecular Karyotyping of Human Single Sperm by Array- Comparative Genomic Hybridization

No valid method is currently available to analyze the entire genome of sperm, including aneuploidies and structural chromosomal alterations. Here we describe the optimization and application of array-Comparative Genomic Hybridization (aCGH) on single human sperm. The aCGH procedure involves screenin...

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Autors principals: Patassini, Cristina, Garolla, Andrea, Bottacin, Alberto, Menegazzo, Massimo, Speltra, Elena, Foresta, Carlo, Ferlin, Alberto
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614952/
https://ncbi.nlm.nih.gov/pubmed/23565289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060922
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