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Molecular Karyotyping of Human Single Sperm by Array- Comparative Genomic Hybridization

No valid method is currently available to analyze the entire genome of sperm, including aneuploidies and structural chromosomal alterations. Here we describe the optimization and application of array-Comparative Genomic Hybridization (aCGH) on single human sperm. The aCGH procedure involves screenin...

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Bibliografiske detaljer
Main Authors: Patassini, Cristina, Garolla, Andrea, Bottacin, Alberto, Menegazzo, Massimo, Speltra, Elena, Foresta, Carlo, Ferlin, Alberto
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614952/
https://ncbi.nlm.nih.gov/pubmed/23565289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060922
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