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Molecular Karyotyping of Human Single Sperm by Array- Comparative Genomic Hybridization

No valid method is currently available to analyze the entire genome of sperm, including aneuploidies and structural chromosomal alterations. Here we describe the optimization and application of array-Comparative Genomic Hybridization (aCGH) on single human sperm. The aCGH procedure involves screenin...

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Bibliografische gegevens
Hoofdauteurs: Patassini, Cristina, Garolla, Andrea, Bottacin, Alberto, Menegazzo, Massimo, Speltra, Elena, Foresta, Carlo, Ferlin, Alberto
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614952/
https://ncbi.nlm.nih.gov/pubmed/23565289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060922
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