Tumor VEGF:VEGFR2 autocrine feed-forward loop triggers angiogenesis in lung cancer

The molecular mechanisms that control the balance between antiangiogenic and proangiogenic factors and initiate the angiogenic switch in tumors remain poorly defined. By combining chemical genetics with multimodal imaging, we have identified an autocrine feed-forward loop in tumor cells in which tum...

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מידע ביבליוגרפי
Main Authors: Chatterjee, Sampurna, Heukamp, Lukas C., Siobal, Maike, Schöttle, Jakob, Wieczorek, Caroline, Peifer, Martin, Frasca, Davide, Koker, Mirjam, König, Katharina, Meder, Lydia, Rauh, Daniel, Buettner, Reinhard, Wolf, Jürgen, Brekken, Rolf A., Neumaier, Bernd, Christofori, Gerhard, Thomas, Roman K., Ullrich, Roland T.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Clinical Investigation 2013
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613914/
https://ncbi.nlm.nih.gov/pubmed/23454747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65385
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