Glomerular Structure and Function Require Paracrine, Not Autocrine, VEGF–VEGFR-2 Signaling

VEGF is a potent vascular growth factor produced by podocytes in the developing and mature glomerulus. Specific deletion of VEGF from podocytes causes glomerular abnormalities including profound endothelial cell injury, suggesting that paracrine signaling is critical for maintaining the glomerular f...

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Detaylı Bibliyografya
Asıl Yazarlar: Sison, Karen, Eremina, Vera, Baelde, Hans, Min, Wang, Hirashima, Masanori, Fantus, I. George, Quaggin, Susan E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Nephrology 2010
Konular:
Basic Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013545/
https://ncbi.nlm.nih.gov/pubmed/20688931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010030295
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