Autocrine stimulation of VEGFR-2 activates human leukemic cell growth and migration

Emerging data suggest that VEGF receptors are expressed by endothelial cells as well as hematopoietic stem cells. Therefore, we hypothesized that functional VEGF receptors may also be expressed in malignant counterparts of hematopoietic stem cells such as leukemias. We demonstrate that certain leuke...

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Detalhes bibliográficos
Main Authors: Dias, Sergio, Hattori, Koichi, Zhu, Zhenping, Heissig, Beate, Choy, Margaret, Lane, William, Wu, Yan, Chadburn, Amy, Hyjek, Elizabeth, Gill, Muhammad, Hicklin, Daniel J., Witte, Larry, Moore, M.A.S., Rafii, Shahin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2000
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC380247/
https://ncbi.nlm.nih.gov/pubmed/10953026
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