Epitope specificity determines pathogenicity and detectability in ANCA-associated vasculitis

Anti-neutrophil cytoplasmic antibody–associated (ANCA-associated) small vessel necrotizing vasculitis is caused by immune-mediated inflammation of the vessel wall and is diagnosed in some cases by the presence of myeloperoxidase-specific antibodies (MPO-ANCA). This multicenter study sought to determ...

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Main Authors: Roth, Aleeza J., Ooi, Joshua D., Hess, Jacob J., van Timmeren, Mirjan M., Berg, Elisabeth A., Poulton, Caroline E., McGregor, JulieAnne, Burkart, Madelyn, Hogan, Susan L., Hu, Yichun, Winnik, Witold, Nachman, Patrick H., Stegeman, Coen A., Niles, John, Heeringa, Peter, Kitching, A. Richard, Holdsworth, Stephen, Jennette, J. Charles, Preston, Gloria A., Falk, Ronald J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613913/
https://ncbi.nlm.nih.gov/pubmed/23549081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65292
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