Epitope specificity determines pathogenicity and detectability in ANCA-associated vasculitis

Anti-neutrophil cytoplasmic antibody–associated (ANCA-associated) small vessel necrotizing vasculitis is caused by immune-mediated inflammation of the vessel wall and is diagnosed in some cases by the presence of myeloperoxidase-specific antibodies (MPO-ANCA). This multicenter study sought to determ...

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Detalhes bibliográficos
Main Authors: Roth, Aleeza J., Ooi, Joshua D., Hess, Jacob J., van Timmeren, Mirjan M., Berg, Elisabeth A., Poulton, Caroline E., McGregor, JulieAnne, Burkart, Madelyn, Hogan, Susan L., Hu, Yichun, Winnik, Witold, Nachman, Patrick H., Stegeman, Coen A., Niles, John, Heeringa, Peter, Kitching, A. Richard, Holdsworth, Stephen, Jennette, J. Charles, Preston, Gloria A., Falk, Ronald J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613913/
https://ncbi.nlm.nih.gov/pubmed/23549081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65292
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