Epitope specificity determines pathogenicity and detectability in ANCA-associated vasculitis

Anti-neutrophil cytoplasmic antibody–associated (ANCA-associated) small vessel necrotizing vasculitis is caused by immune-mediated inflammation of the vessel wall and is diagnosed in some cases by the presence of myeloperoxidase-specific antibodies (MPO-ANCA). This multicenter study sought to determ...

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Autores principales: Roth, Aleeza J., Ooi, Joshua D., Hess, Jacob J., van Timmeren, Mirjan M., Berg, Elisabeth A., Poulton, Caroline E., McGregor, JulieAnne, Burkart, Madelyn, Hogan, Susan L., Hu, Yichun, Winnik, Witold, Nachman, Patrick H., Stegeman, Coen A., Niles, John, Heeringa, Peter, Kitching, A. Richard, Holdsworth, Stephen, Jennette, J. Charles, Preston, Gloria A., Falk, Ronald J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613913/
https://ncbi.nlm.nih.gov/pubmed/23549081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65292
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