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PQBP1, a factor linked to intellectual disability, affects alternative splicing associated with neurite outgrowth
Polyglutamine-binding protein 1 (PQBP1) is a highly conserved protein associated with neurodegenerative disorders. Here, we identify PQBP1 as an alternative messenger RNA (mRNA) splicing (AS) effector capable of influencing splicing of multiple mRNA targets. PQBP1 is associated with many splicing fa...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3613609/ https://ncbi.nlm.nih.gov/pubmed/23512658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.212308.112 |
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