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PQBP1, a factor linked to intellectual disability, affects alternative splicing associated with neurite outgrowth

Polyglutamine-binding protein 1 (PQBP1) is a highly conserved protein associated with neurodegenerative disorders. Here, we identify PQBP1 as an alternative messenger RNA (mRNA) splicing (AS) effector capable of influencing splicing of multiple mRNA targets. PQBP1 is associated with many splicing fa...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Wang, Qingqing, Moore, Michael J., Adelmant, Guillaume, Marto, Jarrod A., Silver, Pamela A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613609/
https://ncbi.nlm.nih.gov/pubmed/23512658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.212308.112
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