PQBP1, a factor linked to intellectual disability, affects alternative splicing associated with neurite outgrowth

Polyglutamine-binding protein 1 (PQBP1) is a highly conserved protein associated with neurodegenerative disorders. Here, we identify PQBP1 as an alternative messenger RNA (mRNA) splicing (AS) effector capable of influencing splicing of multiple mRNA targets. PQBP1 is associated with many splicing fa...

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Bibliographic Details
Main Authors: Wang, Qingqing, Moore, Michael J., Adelmant, Guillaume, Marto, Jarrod A., Silver, Pamela A.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2013
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613609/
https://ncbi.nlm.nih.gov/pubmed/23512658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.212308.112
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