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An Alternative Splicing Network Links Cell Cycle Control to Apoptosis

Alternative splicing is a vast source of biological regulation and diversity that is misregulated in cancer and other diseases. To investigate global control of alternative splicing in human cells, we analyzed splicing of mRNAs encoding Bcl2-family apoptosis factors in a genome-wide siRNA screen. Th...

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Hlavní autoři: Moore, Michael J., Wang, Qingqing, Kennedy, Caleb J., Silver, Pamela A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924962/
https://ncbi.nlm.nih.gov/pubmed/20705336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.07.019
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