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An Alternative Splicing Network Links Cell Cycle Control to Apoptosis

Alternative splicing is a vast source of biological regulation and diversity that is misregulated in cancer and other diseases. To investigate global control of alternative splicing in human cells, we analyzed splicing of mRNAs encoding Bcl2-family apoptosis factors in a genome-wide siRNA screen. Th...

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Bibliografiske detaljer
Main Authors: Moore, Michael J., Wang, Qingqing, Kennedy, Caleb J., Silver, Pamela A.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924962/
https://ncbi.nlm.nih.gov/pubmed/20705336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.07.019
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