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Positional editing of transmembrane domains during ion channel assembly

The integration of transmembrane (TM)-spanning regions of many channels and ion transporters is potentially compromised by the presence of polar and charged residues required for biological function. Although the two TMs of the ATP-gated ion channel subunit P2X2 each contain charged/polar amino acid...

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Detalhes bibliográficos
Main Authors: Öjemalm, Karin, Watson, Helen R., Roboti, Peristera, Cross, Benedict C. S., Warwicker, Jim, von Heijne, Gunnar, High, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613178/
https://ncbi.nlm.nih.gov/pubmed/23230148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.111773
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