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Mutant Human Myocilin Induces Strain Specific Differences in Ocular Hypertension and Optic Nerve Damage in Mice

Elevated intraocular pressure (IOP) is a causative risk factor for the development and progression of glaucoma. Glaucomatous mutations in myocilin (MYOC) damage the trabecular meshwork and elevate IOP in humans and in mice. Animal models of glaucoma are important to discover and better understand mo...

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מידע ביבליוגרפי
Main Authors: McDowell, Colleen M., Luan, Tomi, Zhang, Zhang, Putliwala, Tasneem, Wordinger, Robert J., Millar, J. Cameron, John, Simon W.M., Pang, Iok-Hou, Clark, Abbot F.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612883/
https://ncbi.nlm.nih.gov/pubmed/22575566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2012.04.016
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