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ABCA1 dimer–monomer interconversion during HDL generation revealed by single-molecule imaging

The generation of high-density lipoprotein (HDL), one of the most critical events for preventing atherosclerosis, is mediated by ATP-binding cassette protein A1 (ABCA1). ABCA1 is known to transfer cellular cholesterol and phospholipids to apolipoprotein A-I (apoA-I) for generating discoidal HDL (dHD...

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Main Authors: Nagata, Koh O., Nakada, Chieko, Kasai, Rinshi S., Kusumi, Akihiro, Ueda, Kazumitsu
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612634/
https://ncbi.nlm.nih.gov/pubmed/23479619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220703110
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