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Full characterization of GPCR monomer–dimer dynamic equilibrium by single molecule imaging
Receptor dimerization is important for many signaling pathways. However, the monomer–dimer equilibrium has never been fully characterized for any receptor with a 2D equilibrium constant as well as association/dissociation rate constants (termed super-quantification). Here, we determined the dynamic...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3101103/ https://ncbi.nlm.nih.gov/pubmed/21300851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201009128 |
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