Full characterization of GPCR monomer–dimer dynamic equilibrium by single molecule imaging

Receptor dimerization is important for many signaling pathways. However, the monomer–dimer equilibrium has never been fully characterized for any receptor with a 2D equilibrium constant as well as association/dissociation rate constants (termed super-quantification). Here, we determined the dynamic...

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Autors principals: Kasai, Rinshi S., Suzuki, Kenichi G. N., Prossnitz, Eric R., Koyama-Honda, Ikuko, Nakada, Chieko, Fujiwara, Takahiro K., Kusumi, Akihiro
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2011
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101103/
https://ncbi.nlm.nih.gov/pubmed/21300851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201009128
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