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Evaluation of Arsenic Trioxide by the Pediatric Preclinical Testing Program with a Focus on Ewing Sarcoma

Arsenic trioxide was tested against the PPTP in vitro panel (1.0 nM to 10 μM) and against the PPTP Ewing sarcoma in vivo panel administered intraperitoneally at a dose of 2.5 mg/kg daily × 5 per week for a planned treatment duration of 3 weeks. Arsenic trioxide showed a median relative IC(50) value...

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書誌詳細
主要な著者: Smith, Malcolm A., Kang, Min H., Reynolds, C. Patrick, Kurmasheva, Raushan T., Alexander, Denise, Billups, Catherine A., Toretsky, Jeffrey A., Houghton, Peter J.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612422/
https://ncbi.nlm.nih.gov/pubmed/22315235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.23391
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