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Isolation and characterization of a new mutant human cell line unresponsive to alpha and beta interferons.

Previously we described human cell line 2fTGH, in which expression of guanine phosphoribosyltransferase is tightly controlled by the upstream region of interferon (IFN)-stimulated human gene 6-16. After mutagenesis of 2fTGH and selection with 6-thioguanine and IFN-alpha, we isolated 11.1, a recessiv...

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Publicat a:Mol Cell Biol
Autors principals: John, J, McKendry, R, Pellegrini, S, Flavell, D, Kerr, I M, Stark, G R
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1991
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361241/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1906577/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.8.4189-4195.1991
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