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Isolation and characterization of a new mutant human cell line unresponsive to alpha and beta interferons.

Previously we described human cell line 2fTGH, in which expression of guanine phosphoribosyltransferase is tightly controlled by the upstream region of interferon (IFN)-stimulated human gene 6-16. After mutagenesis of 2fTGH and selection with 6-thioguanine and IFN-alpha, we isolated 11.1, a recessiv...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Principais autores: John, J, McKendry, R, Pellegrini, S, Flavell, D, Kerr, I M, Stark, G R
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 1991
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361241/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1906577/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.8.4189-4195.1991
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