Isolation and characterization of a new mutant human cell line unresponsive to alpha and beta interferons.

Previously we described human cell line 2fTGH, in which expression of guanine phosphoribosyltransferase is tightly controlled by the upstream region of interferon (IFN)-stimulated human gene 6-16. After mutagenesis of 2fTGH and selection with 6-thioguanine and IFN-alpha, we isolated 11.1, a recessiv...

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Autores principales: John, J, McKendry, R, Pellegrini, S, Flavell, D, Kerr, I M, Stark, G R
Formato: Artigo
Lenguaje:Inglês
Publicado: 1991
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC361241/
https://ncbi.nlm.nih.gov/pubmed/1906577
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