Brain regional correlation of amyloid-β with synapses and apolipoprotein E in non-demented individuals: potential mechanisms underlying regional vulnerability to amyloid-β accumulation

To reveal the underlying mechanisms responsible for the regional vulnerability to amyloid-β (Aβ) accumulation prior to the development of Alzheimer’s disease, we studied distribution of Aβ, apolipoprotein E (apoE), synaptic markers, and other molecules involved in Aβ metabolism in multiple brain are...

Full description

Saved in:
Bibliographic Details
Main Authors: Shinohara, Mitsuru, Petersen, Ronald C., Dickson, Dennis W., Bu, Guojun
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612369/
https://ncbi.nlm.nih.gov/pubmed/23371365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-013-1086-9
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items