Cargando...

Dominant inhibitory Ras mutants selectively inhibit the activity of either cellular or oncogenic Ras.

Two dominant inhibitory Ras mutant proteins were analyzed by microinjection. One, [Asn-17]Ras, had a substitution in the putative Mg(2+)-binding site of Ha-Ras. The other, RAST, had a mutation in a yeast RAS protein that impaired its GTPase activity and increased its affinity for GAP. RAST also had...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Stacey, D W, Feig, L A, Gibbs, J B
Formato: Artigo
Idioma:Inglês
Publicado: 1991
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC361212/
https://ncbi.nlm.nih.gov/pubmed/2072908
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!