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Promoter Methylation Regulates SAMHD1 Gene Expression in Human CD4(+) T Cells
The retrovirus restriction factor SAMHD1 is the first identified mammalian dNTP triphosphohydrolase that is highly expressed in human myeloid lineage cells and CD4(+) T lymphocytes. Although SAMHD1 expression is variable in human cell lines and tissue types, mechanisms underlying SAMHD1 gene regulat...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3610999/ https://ncbi.nlm.nih.gov/pubmed/23426363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.447201 |
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